George and Derek work together, Denny still doesn’t have a heart, and Meredith gets paired with Callie. A 12-week pregnant girl dies in the O.R. and her parents try to…

Leonard and Koothrappali escort a heartbroken Wolowitz to Las Vegas, and Sheldon becomes locked out of his apartment and must stay with Penny.

Quentin nears what could be a dead end to his problem; Eliot risks his life for his kingdom, and Margo makes a costly bargain to protect him; Julia, Kady and…

The staff attends to an intern from another hospital who has short-term memory loss. This intern, named Marshall, also has caused a car accident that involved a married couple, their…

Season 1 of How I Met Your Mother premiered on September 19, 2005. When Ted’s best friend Marshall proposes to his girlfriend, Lily, Ted realizes he’d better get a move…

A fellow comic book enthusiast’s hitting on Penny leads to Leonard and Howard going to a bar’s Ladies’ Night.

Addison’s patient is a Catholic mother of seven. Addison gets in trouble after learning that the patient’s husband won’t use contraceptives. Derek treats a divorce attorney who asks if Derek…

Penny squares off with a new beautiful female neighbor who may become the building’s “new Penny.”

Penny’s home business turns into a complete nightmare when Sheldon takes over.

Sam and other “special children” are abducted by the Yellow-Eyed Demon and taken to a ghost town, where the ultimate battle must start.

Harvey’s former mentor turns to him for help when his office comes under investigation. Meanwhile, Jenny suspects Mike may be occupied with more than just his job.

A tragic mistake forces the government to change tactics in the fight against Pablo. But Pablo faces bigger threats from inside his empire.

Rick and Carl find the farm in jeopardy; the group is split up in the chaos; Rick’s leadership is questioned.

Meredith and Izzie take up knitting. Derek operates on Andrew, a spelling bee champ with a serious head injury. Bailey gets in on Andrew’s surgery because she’s worried that her…

Leonard, Sheldon and Wolowitz are ecstatic to learn that a famous science-fiction actress (Summer Glau) is on board the train they are taking to San Francisco.

Dean is attacked by a Djinn… and finds himself in a new reality where his mother is still alive and a mysterious woman holds the key to everything.

Someone dangerous may be loose near the farm; Rick, Shane, Daryl and Glenn keep the group safe.

After a series of deaths at the hospital some of the staff become very superstitious. Izzie worries about Denny and gets confronted by Alex. A patient with OCD drives Cristina…

A paintball game leads to a fight between Sheldon and Penny, and romance for Leslie and Wolowitz.

Madeline receives encouraging news about the play from her director, Joseph Bachman, but is left concerned by his newly icy demeanor. Principal Nippal and Ms. Barnes share their conclusions about…

Rick sides with Shane causing Dale to worry that the group is losing its humanity; Carl’s actions have unintended consequences.

The doctors are up to their necks in their usual levels of drama. Meredith is dealing with the backlash of sleeping with George, George and Burke are bonding in ways…

Leonard and Penny are drawn together after a disastrous visit from Leonard’s mother.

Rick and Shane are in conflict over the fate of an outsider; Andrea helps Hershel’s daughter face a crucial decision.

Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what’s up. Derek and Addison are experiencing their own…

Sheldon’s solution to Penny’s financial difficulty leads to a confrontation between Leonard and Penny’s ex-boyfriend.

Margo feels the pressure of ruling; Julia’s friends question her behavior; Quentin faces the repercussions of the deal he made; Penny finds a way to help Kady.

Rick, Hershel and Glen are trapped and fight to survive; Shane finds Lori in danger.

Derek and Addison’s relationship is rocked to the core when a former friend comes to Seattle Grace and his presence promises to shake things up for a few members of…

Sheldon creates a scientific procedure for making friends.

Rick and the others try to restore order in the aftermath of a terrible discovery. Hershel takes up an old habit and disappears, Rick and Glenn must follow him into…

Derek is still operating when he finds out about Meredith’s current situation. Meredith is freaking out about her situation. Webber and Bailey are dealing with medical health issues. Cristina and…

Penny’s criticism of Wolowitz’s romantic life pushes him into depression and AWOL for a fighting robot battle the rest of guys are depending on him for.

Hershel sets a deadline. All secrets are out in the open. Glenn stands up for himself and Shane takes charge.

An explosive case arrives at the O.R. that might endanger all the lives of the people working there, which leads Dr. Burke to declare a “Code Black” for the hospital….

Harvey must fire an accountant for falsifying his credentials, but Mike finds a more sinister motive for his termination and becomes concerned about his own employment. Meanwhile, Louis thinks he’s…

Pablo goes into hiding as the political tide turns against him, but he finds a way to strike back. Murphy and Peña finally get the CIA to help them.

Secrets are told and secrets are revealed. Hershel refuses to acknowledge the world’s new reality. Andrea comes out of her shell. Everyone is becoming more and more aware that “everything…

All the nurses at Seattle Grace Hospital go on strike, leaving the doctors to fend for themselves. George refuses to cross the picket line and finally joins the nurses on…

Leonard asks Penny for advice when his new relationship starts moving too fast.